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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

  • Melperone hydrochloride EI1650

    Melperone hydrochloride是5-HT2A/D2 受体拮抗剂， 安定精神作用。

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  • Mephedrone hydrochloride EI1655

    Mephedrone hydrochloride是抑制 synaptosomal dopamine，5-HT uptake inhibitor（摄取抑制剂）。

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  • Lithium carbonate EI1551

    Lithium carbonate是情绪稳定剂（Mood stabilizer，Na+/K+ ATPase pump activity）。

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  • LE 300 EI1528

    LE 300是活性的，选择性 dopamine D1 拮抗剂。

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  • Lansoprazole EI1504

    Lansoprazole是H+，K+-ATPase 抑制剂。

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