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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

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    Ro 10-5824 dihydrochloride是选择性 D4 受体部分激动剂。

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  • Raclopride EI2310

    Raclopride是活性选择性 D2/D3 拮抗剂。

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  • Quetiapine hemifumarate EI2287

    Quetiapine hemifumarate是5-HT2/D2 拮抗剂具有抗精神病活性（atypical antipsychotic）。

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  • Prochlorperazine dimaleate EI2235

    Prochlorperazine dimaleate是D2 受体拮抗剂。 也是5-HT3 和 nAChR 的拮抗剂。

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  • Pramipexole dihydrochloride EI2225

    Pramipexole dihydrochloride是选择性D3激动剂。

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