GABA Receptor
GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. GABA receptors influence cognition by coordinating with glutamatergic processes. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels; whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors. A subclass of ionotropic GABA receptors, insensitive to typical allosteric modulators of GABAA receptor channels such as benzodiazepines and barbiturates, designated GABAС receptor.
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Ganaxolone是活性的GABAA受体阳性变构的调节剂（positive allosteric modulator）。
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Gabapentin是抗惊厥剂， Increases brain GABA。
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Furosemide是Na+/2Cl-/K+ (NKCC) symporter 抑制剂。 也是 GABAA的拮抗剂。
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Flurizan是γ-secretase 抑制剂， 在体外降低 Aβ42的水平。
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ETP 45658是活性的 PI 3-激酶 抑制剂， 也抑制 DNA-PK，mTOR。
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Ganaxolone是活性的GABAA受体阳性变构的调节剂（positive allosteric modulator）。
More
-
Gabapentin是抗惊厥剂， Increases brain GABA。
More
-
Furosemide是Na+/2Cl-/K+ (NKCC) symporter 抑制剂。 也是 GABAA的拮抗剂。
More
-
Flurizan是γ-secretase 抑制剂， 在体外降低 Aβ42的水平。
More
-
ETP 45658是活性的 PI 3-激酶 抑制剂， 也抑制 DNA-PK，mTOR。
More
