ATPase


ATPases(adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur. This process is widely used in all known forms of life. Transmembrane ATPases import many of the metabolites necessary for cell metabolism and export toxins, wastes, and solutes that can hinder cellular processes. 
  • Digoxin EY0720

    Digoxin用来治疗不能由其他药物控制的各种心脏疾病,如心房颤动,心房扑动,及心脏衰竭。

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  • Dynasore EY0701

    Dynasore是一种可渗透细胞的,可逆的,非竞争性的dynamin(发动蛋白)抑制剂,抑制dynamin 1/2的GTPase活性,IC50为15 μM,也抑制线粒体dynamin Drp1,对其他小GTP酶没有作用效果。

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  • Bafilomycin A1 EY2004

    Bafilomycin A1是一种液泡H+-ATPase抑制剂,IC50为0.44 nM。

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  • Sodium orthovanadate EY1493

    Sodium orthovanadate是蛋白酪氨酸磷酸酶,碱性磷酸酶和一些ATP酶的抑制剂,最有可能充当磷酸盐类似物。

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  • Golgicide A EY1306

    Golgicide A是一种有效的,快速可逆的GBF1抑制剂。

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