AMPAR


AMPAR (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS). AMPARs are found in many parts of the brain and are the most commonly found receptor in the nervous system. The AMPA receptor GluA2 (GluR2) tetramer was the first glutamate receptor ion channel to be crystallized.
  • Silodosin EY2258

    Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. Silodosin causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it causes practically no orthostatic hypotension (in contrast to other α1 blockers).

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  • Tizanidine HCl EY2245

    Tizanidine HCl is a skeletal muscle relaxant. It is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.

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  • Asenapine EY2232

    Asenapine inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.

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  • IDRA 21 EI1335

    IDRA 21是抑制 AMPA 受体脱敏(inhibit desensitization)。

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  • IEM 1460 EI1336

    IEM 1460是IEM 1460 is an AMPA currents' open-channel blocker and selective for non-GluR2-containing receptors.。

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  • Silodosin EY2258

    Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. Silodosin causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it causes practically no orthostatic hypotension (in contrast to other α1 blockers).

    More
  • Tizanidine HCl EY2245

    Tizanidine HCl is a skeletal muscle relaxant. It is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.

    More
  • Asenapine EY2232

    Asenapine inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.

    More
  • IDRA 21 EI1335

    IDRA 21是抑制 AMPA 受体脱敏(inhibit desensitization)。

    More
  • IEM 1460 EI1336

    IEM 1460是IEM 1460 is an AMPA currents' open-channel blocker and selective for non-GluR2-containing receptors.。

    More
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