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AMPAR


AMPAR (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS). AMPARs are found in many parts of the brain and are the most commonly found receptor in the nervous system. The AMPA receptor GluA2 (GluR2) tetramer was the first glutamate receptor ion channel to be crystallized.

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    Carvedilol是非选择性β和α1阻断剂，能抑制LDL的氧化，IC50为3.8 μM。

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  • IEM 1754 2HBr EY1603

    IEM 1754 dihydrobroMide是一种选择性AMPA/kainate受体抑制剂，作用于GluR1和GluR3，IC50为6 μM。

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    Xylazine hydrochloride (盐酸甲苯噻嗪) 是α2肾上腺素受体激动剂。

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  • Phenylephrine HCl EY1447

    (R)-(-)-Phenylephrine 盐酸盐是α1-肾上腺受体激动剂。

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  • Carvedilol EY1594

    Carvedilol是非选择性β和α1阻断剂，能抑制LDL的氧化，IC50为3.8 μM。

    More

  • IEM 1754 2HBr EY1603

    IEM 1754 dihydrobroMide是一种选择性AMPA/kainate受体抑制剂，作用于GluR1和GluR3，IC50为6 μM。

    More

  • Naftopidil EY1501

    Naftopidil 是选择性α1-肾上腺素能受体拮抗剂，或α受体抑制剂，Ki为58.3 nM。

    More

  • Xylazine HCl EY1486

    Xylazine hydrochloride (盐酸甲苯噻嗪) 是α2肾上腺素受体激动剂。

    More

  • Phenylephrine HCl EY1447

    (R)-(-)-Phenylephrine 盐酸盐是α1-肾上腺受体激动剂。

    More
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