HIF
HIF (Hypoxia-inducible factors) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia.Hypoxia often keeps cells from differentiating. However, hypoxia promotes the formation of blood vessels, and is important for the formation of a vascular system in embryos, and cancer tumors. The hypoxia in wounds also promotes the migration of keratinocytes and the restoration of the epithelium.
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TC-S 7009是高亲和性，选择性 HIF-2α 抑制剂。
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ML 228是HIF 信号通路激动剂。
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BAY 87-2243是低氧诱导的HIF-1抑制剂，IC50为2.0 nM。
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FG-4592是一种HIF α脯氨酰羟化酶抑制剂，能够稳定HIF-2，同时诱导EPO产生。
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Dimethyloxallyl Glycine(DMOG)是可渗透入细胞的HIF-1α脯氨酰羟化酶（HIF-PH）竞争性抑制剂。
More
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TC-S 7009是高亲和性，选择性 HIF-2α 抑制剂。
More
-
ML 228是HIF 信号通路激动剂。
More
-
BAY 87-2243是低氧诱导的HIF-1抑制剂，IC50为2.0 nM。
More
-
FG-4592是一种HIF α脯氨酰羟化酶抑制剂，能够稳定HIF-2，同时诱导EPO产生。
More
-
Dimethyloxallyl Glycine(DMOG)是可渗透入细胞的HIF-1α脯氨酰羟化酶（HIF-PH）竞争性抑制剂。
More
