Home > Signal Pathway > Epigenetics > DNA Methyltransferase

DNA Methyltransferase


DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA. DNA methylation serves a wide variety of biological functions. All the known DNA methyltransferases use S-adenosyl methionine (SAM) as the methyl donor. Three active DNA methyltransferases have been identified in mammals. They are named DNMT1, DNMT3A, and DNMT3B. A fourth enzyme previously known as DNMT2 is not a DNA methyltransferase.

  • Thioguanine EY1340

    Thioguanine是一种嘌呤类的抗代谢药物，广泛用于治疗急性淋巴细胞白血病，自身免疫性疾病（如克罗恩氏病，类风湿关节炎）和器官移植接受患者。

    More

  • Disulfiram EY0332

    Disulfiram是氨基甲酸酯衍生物，可作用于多巴胺-β-羟化酶。

    More
    • Current page2, Total Pages2, Total Record7 First Prev 12 Next Last Goto
More