PPAR


PPARs (peroxisome proliferator-activated receptors) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis of higher organisms.
  • T0070907 EY0423

    T0070907 (T007), a potent and selective PPARγ inhibitor, can reduce α and β tubulin proteins in some cancer cell lines. T0070907是一种选择性的PPARγ抑制剂,IC50为1 nM,比作用于PPARα和PPARδ选择性高800倍以上。

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  • WY-14643 EY0400

    WY-14643 (Pirinixic Acid), a moderate dual PPARα/γ activator, inhibits neuroinflammation and oxidative stress, and also possesses antidepressive activities. WY-14643 (Pirinixic Acid)是一种有效的过氧化物酶体增殖子和PPARα激活剂,EC50为1.5 μM。

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  • GSK3787 EY0336

    GSK3787 is a selective and irreversible PPARβ/δ antagonist with good pharmacokinetic properties. GSK3787是不可逆的PPARδ选择性拮抗剂,pIC50为6.6,对hPPARα和hPPARγ无亲和力。

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  • Naringenin EY1651

    Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines.

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  • Clofibric Acid EY1112

    Clofibric Acid是PPARα激动剂,是一种降血脂剂。

    More
  • T0070907 EY0423

    T0070907 (T007), a potent and selective PPARγ inhibitor, can reduce α and β tubulin proteins in some cancer cell lines. T0070907是一种选择性的PPARγ抑制剂,IC50为1 nM,比作用于PPARα和PPARδ选择性高800倍以上。

    More
  • WY-14643 EY0400

    WY-14643 (Pirinixic Acid), a moderate dual PPARα/γ activator, inhibits neuroinflammation and oxidative stress, and also possesses antidepressive activities. WY-14643 (Pirinixic Acid)是一种有效的过氧化物酶体增殖子和PPARα激活剂,EC50为1.5 μM。

    More
  • GSK3787 EY0336

    GSK3787 is a selective and irreversible PPARβ/δ antagonist with good pharmacokinetic properties. GSK3787是不可逆的PPARδ选择性拮抗剂,pIC50为6.6,对hPPARα和hPPARγ无亲和力。

    More
  • Naringenin EY1651

    Naringenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess strong anti-proliferative properties and the ability to induce apoptosis in hepatoma cell lines.

    More
  • Clofibric Acid EY1112

    Clofibric Acid是PPARα激动剂,是一种降血脂剂。

    More
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