mAChR
MAChRs (Muscarinic acetylcholine receptors) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors were named as such because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists.
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(+)-Muscarine iodide是Muscarinic 受体 激动剂。
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Zamifenacin fumarate是选择性 M3 拮抗剂。
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Xanomeline oxalate是选择性M1激动剂。
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VU 0255035是高选择性muscarinic M1受体的拮抗剂。
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VU 0357017 hydrochloride是M1受体阳性变构的调节剂（positive allosteric modulator）。
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(+)-Muscarine iodide是Muscarinic 受体 激动剂。
More
-
Zamifenacin fumarate是选择性 M3 拮抗剂。
More
-
Xanomeline oxalate是选择性M1激动剂。
More
-
VU 0255035是高选择性muscarinic M1受体的拮抗剂。
More
-
VU 0357017 hydrochloride是M1受体阳性变构的调节剂（positive allosteric modulator）。
More
