mAChR
MAChRs (Muscarinic acetylcholine receptors) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors were named as such because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists.
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Ipratropium bromide是Muscarinic 拮抗剂。
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Methscopolamine是一种毒蕈碱型乙酰胆碱受体抑制剂。
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Neostigmine Bromide是胆碱酯酶抑制剂，可作用于重症肌无力。
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Darifenacin hydrobromide (氢溴酸达非那新; UK88525) 是选择性M3蕈毒碱受体拮抗剂，pKi为8.9。
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Gallamine Triethiodide是胆碱能受体抑制剂和非去极化阻断剂，IC50为68.0±8.4 μM。
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Ipratropium bromide是Muscarinic 拮抗剂。
More
-
Methscopolamine是一种毒蕈碱型乙酰胆碱受体抑制剂。
More
-
Neostigmine Bromide是胆碱酯酶抑制剂，可作用于重症肌无力。
More
-
Darifenacin hydrobromide (氢溴酸达非那新; UK88525) 是选择性M3蕈毒碱受体拮抗剂，pKi为8.9。
More
-
Gallamine Triethiodide是胆碱能受体抑制剂和非去极化阻断剂，IC50为68.0±8.4 μM。
More
