GABA Receptor
GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. GABA receptors influence cognition by coordinating with glutamatergic processes. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels; whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors. A subclass of ionotropic GABA receptors, insensitive to typical allosteric modulators of GABAA receptor channels such as benzodiazepines and barbiturates, designated GABAС receptor.
-
L-838，417是具有亚型选择性的 GABAA 部分激动剂。
More
-
L-655，708是苯二氮卓类反向激动剂（Benzodiazepine ），对α5-containing GABAA 受体具有选择性。
More
-
Isoguvacine hydrochloride是选择性GABAA激动剂。
More
-
(+)-Bicuculline是一种竞争性GABAA受体拮抗剂，IC50为2 μM，也抑制Ca(2+)激活的钾离子通道。
More
-
Flumazenil(Ro 15-1788)是非选择性含α1，α2，α3和α5 GABAA受体拮抗剂。
More
-
L-838，417是具有亚型选择性的 GABAA 部分激动剂。
More
-
L-655，708是苯二氮卓类反向激动剂（Benzodiazepine ），对α5-containing GABAA 受体具有选择性。
More
-
Isoguvacine hydrochloride是选择性GABAA激动剂。
More
-
(+)-Bicuculline是一种竞争性GABAA受体拮抗剂，IC50为2 μM，也抑制Ca(2+)激活的钾离子通道。
More
-
Flumazenil(Ro 15-1788)是非选择性含α1，α2，α3和α5 GABAA受体拮抗剂。
More
