Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
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L-Epinephrine Bitartrate是α和β肾上腺素受体刺激剂，是一种激素和神经递质。
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Ivabradine是新的If抑制剂，IC50为2.9μM。
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Carvedilol是非选择性β和α1阻断剂，能抑制LDL的氧化，IC50为3.8 μM。
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Naftopidil 是选择性α1-肾上腺素能受体拮抗剂，或α受体抑制剂，Ki为58.3 nM。
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Xylazine hydrochloride (盐酸甲苯噻嗪) 是α2肾上腺素受体激动剂。
More
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L-Epinephrine Bitartrate是α和β肾上腺素受体刺激剂，是一种激素和神经递质。
More
-
Ivabradine是新的If抑制剂，IC50为2.9μM。
More
-
Carvedilol是非选择性β和α1阻断剂，能抑制LDL的氧化，IC50为3.8 μM。
More
-
Naftopidil 是选择性α1-肾上腺素能受体拮抗剂，或α受体抑制剂，Ki为58.3 nM。
More
-
Xylazine hydrochloride (盐酸甲苯噻嗪) 是α2肾上腺素受体激动剂。
More
