Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
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Zinterol hydrochloride是选择性 β2 激动剂。
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Xamoterol hemifumarate是β1 选择性部分激动剂。
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WB 4101 hydrochloride是α1A 拮抗剂。
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UK 14，304是α2 激动剂。
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Terazosin hydrochloride是α1和α2B 拮抗剂 (α1 > α2B)。 口服有效。
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Zinterol hydrochloride是选择性 β2 激动剂。
More
-
Xamoterol hemifumarate是β1 选择性部分激动剂。
More
-
WB 4101 hydrochloride是α1A 拮抗剂。
More
-
UK 14，304是α2 激动剂。
More
-
Terazosin hydrochloride是α1和α2B 拮抗剂 (α1 > α2B)。 口服有效。
More
