nAChR
nAChRs (Nicotinic acetylcholine receptors) are neuron receptor proteins that respond to the neurotransmitter acetylcholine. They are particularly responsive to nicotine. Nicotinic receptors also respond to drugs, including the nicotinic receptor agonist nicotine. As ionotropic receptors, nAChRs are directly linked to ion channels and do not use second messengers (as metabotropic receptors do). Nicotinic acetylcholine receptors are the best-studied of the ionotropic receptors.
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Prochlorperazine dimaleate是D2 受体拮抗剂。 也是5-HT3 和 nAChR 的拮抗剂。
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PNU 282987是选择性 α7 nAChR 激动剂。
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PHA 543613 hydrochloride是活性的，选择性 α7 nAChR 激动剂。
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NS 9283是α4β2的阳性变构的调节剂（positive allosteric modulator）。
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NS 1738是nAChR阳性变构的调节剂（positive allosteric modulator），体内活性有效。
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