VDAC
VDAC (Voltage-dependent anion channels) are a class of porin ion channel located on the outer mitochondrial membrane. VDAC facilitates the exchange of ions and molecules between mitochondria and cytosol and is regulated by the interactions with other proteins and small molecules. The voltage-dependent ion channel plays a key role in regulating metabolic and energetic flux across the outer mitochondrial membrane.
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Norethindrone is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.
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Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.
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Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation.
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Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
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Methylthiouracil is an antithyroid preparation.
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