Sodium Channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane. They are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change ("Voltage-gated", "voltage-sensitive", or "voltage-dependent" sodium channel also called "VGSCs" or "Nav channel") or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials.
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PF 05089771是活性的，选择性 Nav1.7 通道阻断剂。
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Oxcarbazepine是镇惊活性， 抑制 Na+通道活性。
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Olopatadine hydrochloride是H1 拮抗剂， 眼部抗过敏剂。
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NAV 26是选择性 Nav1.7 通道阻断剂。
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Mepyramine maleate是选择性 H1 反向激动剂。
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