SGLT
SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose.
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L-AP4是选择性 group III mGlu 激动剂。
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L-732，138是活性选择性 NK1 拮抗剂。
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L-733，060 hydrochloride是活性的 NK1 拮抗剂。
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L 760735是高亲和性 NK1 受体拮抗剂。
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JNJ 16259685是极高活性的 mGlu1-选择性非竞争性拮抗剂。
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-
L-AP4是选择性 group III mGlu 激动剂。
More
-
L-732，138是活性选择性 NK1 拮抗剂。
More
-
L-733，060 hydrochloride是活性的 NK1 拮抗剂。
More
-
L 760735是高亲和性 NK1 受体拮抗剂。
More
-
JNJ 16259685是极高活性的 mGlu1-选择性非竞争性拮抗剂。
More
-
L-AP4是选择性 group III mGlu 激动剂。
More
-
L-732，138是活性选择性 NK1 拮抗剂。
More
-
L-733，060 hydrochloride是活性的 NK1 拮抗剂。
More
-
L 760735是高亲和性 NK1 受体拮抗剂。
More
-
JNJ 16259685是极高活性的 mGlu1-选择性非竞争性拮抗剂。
More
