SGLT
SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose.
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ZJ 43是Glutamate carboxypeptidase II，III (NAALADase， NAAG peptidase) 抑制剂。
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Z-Cyclopentyl-AP4是Group III mGlu的激动剂 (mGlu4 > mGlu8 > mGlu7)。
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YM 298198 hydrochloride是高活性选择性非竞争性的mGlu1拮抗剂。
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YM 230888是选择性mGlu1拮抗剂。
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XAP 044是活性的，选择性 mGlu7 拮抗剂。
More
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ZJ 43是Glutamate carboxypeptidase II，III (NAALADase， NAAG peptidase) 抑制剂。
More
-
Z-Cyclopentyl-AP4是Group III mGlu的激动剂 (mGlu4 > mGlu8 > mGlu7)。
More
-
YM 298198 hydrochloride是高活性选择性非竞争性的mGlu1拮抗剂。
More
-
YM 230888是选择性mGlu1拮抗剂。
More
-
XAP 044是活性的，选择性 mGlu7 拮抗剂。
More
-
ZJ 43是Glutamate carboxypeptidase II，III (NAALADase， NAAG peptidase) 抑制剂。
More
-
Z-Cyclopentyl-AP4是Group III mGlu的激动剂 (mGlu4 > mGlu8 > mGlu7)。
More
-
YM 298198 hydrochloride是高活性选择性非竞争性的mGlu1拮抗剂。
More
-
YM 230888是选择性mGlu1拮抗剂。
More
-
XAP 044是活性的，选择性 mGlu7 拮抗剂。
More
