Proton Pump
The proton pump is an integral membrane protein that is capable of moving protons across a biological membrane. Mechanisms are based on conformational changes of the protein structure or on the Q cycle. In cell respiration, the proton pump uses energy to transport protons from the matrix of the mitochondrion to the inter-membrane space. The proton pump does not create energy, but forms a gradient that stores energy for later use.
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APcK 110是KIT 抑制剂。
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(-)-5'-DMH-CBD是Metabolically stable anandamide transport的抑制剂。
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N1,N11-Diethylnorspermine tetrahydrochloride是Spermine,spermidine acetyltransferase的激活剂。
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Miglustat hydrochloride是α-glucosidase I,II 抑制剂。 也抑制 ceramide-specific glycosyltransferases。
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Sunitinib Malate是一种多靶点受体酪氨酸激酶(RTK)抑制剂,作用于VEGFR1, VEGFR2, VEGFR3, PDGFRβ, FLT3,和CSF-1R时,IC50分别为15 nM, 38 nM, 30 nM, 55 nM, 21 nM,和35 nM。
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