Potassium Channel
potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes. Furthermore potassium channels are found in most cell types and control a wide variety of cell functions. These channels act to set or reset the resting potential in many cells. In excitable cells, such as neurons, the delayed counterflow of potassium ions shapes the action potential.
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XE 991 dihydrochloride是活性的， 选择性 KV7 (KCNQ) 通道阻断剂， 可以阻断M电流。
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Y-26763是Kir6 (KATP)通道开启剂（channel opener）。
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Y-27152是是Kir6 (KATP)通道开启剂Y-26763的前药， 口服生物活性保留，在体内有长效的降压活性。。
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VU 591 hydrochloride是选择性 Kir1.1 (ROMK) 抑制剂。
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UK 78282 hydrochloride是KV1.3，KV1.4 通道的阻断剂。
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