P-gp


P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
  • Estriol EY0541

    Estriol是G蛋白偶联雌激素受体拮抗剂,可作用于雌激素受体阴性乳腺癌细胞。

    More
  • Toremifene Citrate EY0492

    Toremifene Citrate 是第二代选择性雌激素受体调节剂,对雌激素受体的IC50为1μM。

    More
  • Baicalin EY0474

    Baicalin is a known prolyl endopeptidase inhibitor that induces apoptosis in pancreatic cancer cells.

    More
  • Estradiol Cypionate EY0482

    Estradiol cypionate是一种合成酯,是长效雌激素。

    More
  • Dapagliflozin EY0416

    Dapagliflozin是口服活性的SGLT2抑制剂,可作用于2型糖尿病。

    More
  • Estriol EY0541

    Estriol是G蛋白偶联雌激素受体拮抗剂,可作用于雌激素受体阴性乳腺癌细胞。

    More
  • Toremifene Citrate EY0492

    Toremifene Citrate 是第二代选择性雌激素受体调节剂,对雌激素受体的IC50为1μM。

    More
  • Baicalin EY0474

    Baicalin is a known prolyl endopeptidase inhibitor that induces apoptosis in pancreatic cancer cells.

    More
  • Estradiol Cypionate EY0482

    Estradiol cypionate是一种合成酯,是长效雌激素。

    More
  • Dapagliflozin EY0416

    Dapagliflozin是口服活性的SGLT2抑制剂,可作用于2型糖尿病。

    More
  • Current page29, Total Pages30, Total Record147 First Prev 2627282930 Next Last Goto