P-gp


P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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    Armodafinil is the R-enantiomer of the racemic synthetic agent modafinil with central nervous system (CNS) stimulant and wakefulness-promoting activities.

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  • Chlorotrianisene EY2714

    Chlorotrianisene is a synthetic, non-steroidal estrogen. It is a selective estrogen receptor modulator.

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    Desogestrel是第三代孕激素类似物。

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    Chlormadinone acetate has antiandrogenic activity. It has been used in combinations as an oral contraceptive. Chlormadinone acetate is a steroidal progestin, with antiandrogen and antiestrogenic effects.

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  • Piperazine EY2677

    Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen in the ring.

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  • Armodafinil EY2725

    Armodafinil is the R-enantiomer of the racemic synthetic agent modafinil with central nervous system (CNS) stimulant and wakefulness-promoting activities.

    More
  • Chlorotrianisene EY2714

    Chlorotrianisene is a synthetic, non-steroidal estrogen. It is a selective estrogen receptor modulator.

    More
  • Desogestrel EY2721

    Desogestrel是第三代孕激素类似物。

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  • Chlormadinone acetate EY2690

    Chlormadinone acetate has antiandrogenic activity. It has been used in combinations as an oral contraceptive. Chlormadinone acetate is a steroidal progestin, with antiandrogen and antiestrogenic effects.

    More
  • Piperazine EY2677

    Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen in the ring.

    More
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