P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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MK 0343是亚型选择性 GABAA 受体部分激动剂。
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Loreclezole hydrochloride是亚型选择性GABAA受体调节剂。
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L-838，417是具有亚型选择性的 GABAA 部分激动剂。
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L-655，708是苯二氮卓类反向激动剂（Benzodiazepine ），对α5-containing GABAA 受体具有选择性。
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KRCA 0008是活性的 Ack1，ALK dual 抑制剂， 口服有效。
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MK 0343是亚型选择性 GABAA 受体部分激动剂。
More
-
Loreclezole hydrochloride是亚型选择性GABAA受体调节剂。
More
-
L-838，417是具有亚型选择性的 GABAA 部分激动剂。
More
-
L-655，708是苯二氮卓类反向激动剂（Benzodiazepine ），对α5-containing GABAA 受体具有选择性。
More
-
KRCA 0008是活性的 Ack1，ALK dual 抑制剂， 口服有效。
More
