P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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rac BHFF是活性选择性 GABAB 阳性变构的调节剂（positive allosteric modulator）。
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PSC 833是P-gp-mediated MDR的抑制剂。
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Primidone是活性的iates GABAA 受体 function。
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Pregnanolone是GABAA 受体阳性变构的调节剂（positive allosteric modulator。
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PHP 501 trifluoroacetate是活性的 GABAA 拮抗剂。
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rac BHFF是活性选择性 GABAB 阳性变构的调节剂（positive allosteric modulator）。
More
-
PSC 833是P-gp-mediated MDR的抑制剂。
More
-
Primidone是活性的iates GABAA 受体 function。
More
-
Pregnanolone是GABAA 受体阳性变构的调节剂（positive allosteric modulator。
More
-
PHP 501 trifluoroacetate是活性的 GABAA 拮抗剂。
More
