P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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THIP hydrochloride是GABAA激动剂。
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TCS 1205是亚型选择性GABAA受体激动剂。
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TB 21007是α5选择性GABAA 反向激动剂。
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SR 95531 hydrobromide是选择性， 竞争性 GABAA 受体拮抗剂。
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SCH 50911是选择性， 竞争性口服有效的GABAB 拮抗剂。
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THIP hydrochloride是GABAA激动剂。
More
-
TCS 1205是亚型选择性GABAA受体激动剂。
More
-
TB 21007是α5选择性GABAA 反向激动剂。
More
-
SR 95531 hydrobromide是选择性， 竞争性 GABAA 受体拮抗剂。
More
-
SCH 50911是选择性， 竞争性口服有效的GABAB 拮抗剂。
More
