P-gp
P-gp (permeability glycoprotein) is an important protein of the cell membrane that pumps many foreign substances out of cells. It is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi and bacteria and likely evolved as a defense mechanism against harmful substances. P-gp is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.
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3-Methyl-GABA是GABA amino-transferase的激动剂。
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2-Hydroxysaclofen是选择性 GABAB 拮抗剂，比saclofen活性更强。。
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17-PA是Neurosteroid activation的拮抗剂，direct gating of GABAA。
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(S)-SNAP 5114是GABA uptake inhibitor（摄取抑制剂）。
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(RS)-Baclofen是选择性 GABAB 激动剂。
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3-Methyl-GABA是GABA amino-transferase的激动剂。
More
-
2-Hydroxysaclofen是选择性 GABAB 拮抗剂，比saclofen活性更强。。
More
-
17-PA是Neurosteroid activation的拮抗剂，direct gating of GABAA。
More
-
(S)-SNAP 5114是GABA uptake inhibitor（摄取抑制剂）。
More
-
(RS)-Baclofen是选择性 GABAB 激动剂。
More
