Oct-4
Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
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BMS 753是RARα-选择性激动剂。
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BMS 493是Pan-RAR 反向激动剂。
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BMS 195614是选择性 RARα 拮抗剂。
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B-HT 920是D2 受体激动剂。 也是 α2 激动剂，5-HT3 拮抗剂。
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Bexarotene是活性的，选择性 RXR 激动剂。
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BMS 753是RARα-选择性激动剂。
More
-
BMS 493是Pan-RAR 反向激动剂。
More
-
BMS 195614是选择性 RARα 拮抗剂。
More
-
B-HT 920是D2 受体激动剂。 也是 α2 激动剂，5-HT3 拮抗剂。
More
-
Bexarotene是活性的，选择性 RXR 激动剂。
More
