Oct-4
Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
-
NGD 94-1是选择性 D4 受体配体。
More
-
NGB 2904是活性的，选择性 D3 拮抗剂。
More
-
Nemonapride是高 活性的 D2样拮抗剂。 也是5-HT1A 激动剂。
More
-
Nafadotride是高活性,竞争性的preferential D3 拮抗剂。（Ki = 0.52, 5, and 269 nM for human cloned D3, D2 and D4 receptors respectively.）
More
-
MM 11253是RARγ-选择性拮抗剂。
More
-
NGD 94-1是选择性 D4 受体配体。
More
-
NGB 2904是活性的，选择性 D3 拮抗剂。
More
-
Nemonapride是高 活性的 D2样拮抗剂。 也是5-HT1A 激动剂。
More
-
Nafadotride是高活性,竞争性的preferential D3 拮抗剂。（Ki = 0.52, 5, and 269 nM for human cloned D3, D2 and D4 receptors respectively.）
More
-
MM 11253是RARγ-选择性拮抗剂。
More
