Oct-4


Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
  • SKF 38393 hydrobromide EI2564

    SKF 38393 hydrobromide是选择性 D1样激动剂。

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  • SCH 39166 hydrobromide EI2508

    SCH 39166 hydrobromide是高亲和性 D1/D5 受体拮抗剂。

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  • SCH 23390 hydrochloride EI2506

    SCH 23390 hydrochloride是经典的选择性 D1样拮抗剂, 也是5-HT2C和5-HT1C的激动剂,Kir3的通道阻断剂。

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  • SB 277011A dihydrochloride EI2477

    SB 277011A dihydrochloride是选择性 D3 拮抗剂。

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  • Roxindole hydrochloride EI2381

    Roxindole hydrochloride是Roxindole hydrochloride is a dopamine D2 autoreceptor agonist and has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter.。

    More
  • SKF 38393 hydrobromide EI2564

    SKF 38393 hydrobromide是选择性 D1样激动剂。

    More
  • SCH 39166 hydrobromide EI2508

    SCH 39166 hydrobromide是高亲和性 D1/D5 受体拮抗剂。

    More
  • SCH 23390 hydrochloride EI2506

    SCH 23390 hydrochloride是经典的选择性 D1样拮抗剂, 也是5-HT2C和5-HT1C的激动剂,Kir3的通道阻断剂。

    More
  • SB 277011A dihydrochloride EI2477

    SB 277011A dihydrochloride是选择性 D3 拮抗剂。

    More
  • Roxindole hydrochloride EI2381

    Roxindole hydrochloride是Roxindole hydrochloride is a dopamine D2 autoreceptor agonist and has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter.。

    More
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