Oct-4
Oct-4 transcription factor(Oct3/4,POU5F1) is initially active as a maternal factor in the oocyte but remains active in embryos throughout the preimplantation period. Oct-4 expression is associated with an undifferentiated phenotype and tumors. Gene knockdown of Oct-4 promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. Oct-4 can form a heterodimer with Sox2, so that these two proteins bind DNA together.
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(±)-MDMA hydrochloride是5-HT，dopamine uptake inhibitor， hallucinogenic activity。
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(±)-McN 5652是活性的， 口服活性的5-HT 吸收抑制剂。体外也能抑制 noradrenalin，dopamine的吸收。
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(+)-UH 232 maleate是D2 自主受体拮抗剂。 也是D3 部分激动剂。
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(+)-PD 128907 hydrochloride是D3 激动剂 (D3 ≥ D2 > D4)。
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(+)-AJ 76 hydrochloride是拮抗剂， 优先作用于 D2-样自主受体。
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(±)-MDMA hydrochloride是5-HT，dopamine uptake inhibitor， hallucinogenic activity。
More
-
(±)-McN 5652是活性的， 口服活性的5-HT 吸收抑制剂。体外也能抑制 noradrenalin，dopamine的吸收。
More
-
(+)-UH 232 maleate是D2 自主受体拮抗剂。 也是D3 部分激动剂。
More
-
(+)-PD 128907 hydrochloride是D3 激动剂 (D3 ≥ D2 > D4)。
More
-
(+)-AJ 76 hydrochloride是拮抗剂， 优先作用于 D2-样自主受体。
More
