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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

  • 3-CPMT EI0264

    3-CPMT是Dopamine uptake inhibitor（摄取抑制剂）。

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  • 2-CMDO EI0242

    2-CMDO是D2样拮抗剂。 展现部分 D4 选择性。

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  • (RS)-(±)-Sulpiride EI0130

    (RS)-(±)-Sulpiride是标准选择性 D2-样拮抗剂。

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  • (R)-(-)-Apomorphine hydrochloride EI0111

    (R)-(-)-Apomorphine hydrochloride是Dopamine 激动剂， 无亚型的选择性。

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  • (±)-MDMA hydrochloride EI0091

    (±)-MDMA hydrochloride是5-HT，dopamine uptake inhibitor， hallucinogenic activity。

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