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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

  • Eticlopride hydrochloride EI1101

    Eticlopride hydrochloride是选择性 D2/D3 拮抗剂。

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  • EIPA EI1066

    EIPA是抑制 TRPP3-mediated currents，也抑制 the Na+/H+ exchanger (NHE)。

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  • Domperidone EI1025

    Domperidone是外周D2样受体拮抗剂(peripheral D2-like)。

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  • Dihydrexidine hydrochloride EI0980

    Dihydrexidine hydrochloride是选择性 D1样激动剂。

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  • D-Amphetamine sulfate EI0926

    D-Amphetamine sulfate是诱导dopamine， 5-HT，noradrenalin的释放。

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