Home > Signal Pathway > Transmembrane Transporters > Ion Pumps/Transporters

Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

  • Rotundine EY1270

    Rotundine是一种选择性多巴胺D1受体拮抗剂， IC50为166 nM。

    More

  • Lurasidone HCl EY1221

    Lurasidone HCl是一种非典型的抗精神病药物，抑制D2， 5-HT2A， 5-HT7， 5-HT1A和去甲肾上腺素α2C，IC50分别为1.68 nM， 2.03 nM， 0.495 nM， 6.75 nM和10.8 nM。

    More

  • Levosulpiride EY0965

    Levosulpiride是Sulpiride的(S)对映体, 是多巴胺D2受体拮抗剂。

    More

  • Pergolide Mesylate EY0810

    Pergolide是有抗帕金森病特性的多巴胺受体激动剂。

    More

  • ME0328 EY0772

    ME0328 是一种高度选择性PARP抑制剂，IC50 为0.89 μM，其作用于PARP3的选择性比作用于PARP1的选择性约高七倍。

    More
    • Current page24, Total Pages25, Total Record125 First Prev 2122232425 Next Last Goto
More