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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

  • NGD 94-1 EI1885

    NGD 94-1是选择性 D4 受体配体。

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  • NGB 2904 EI1884

    NGB 2904是活性的,选择性 D3 拮抗剂。

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  • Nemonapride EI1852

    Nemonapride是高 活性的 D2样拮抗剂。 也是5-HT1A 激动剂。

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  • Nafadotride EI1817

    Nafadotride是高活性,竞争性的preferential D3 拮抗剂。(Ki = 0.52, 5, and 269 nM for human cloned D3, D2 and D4 receptors respectively.)

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  • Mesulergine hydrochloride EI1659

    Mesulergine hydrochloride是5-HT2A 和5-HT2C 拮抗剂。 也是dopamine 受体部分激动剂。

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