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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

  • Sonepiprazole EI2588

    Sonepiprazole是选择性 D4 受体拮抗剂。

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  • SN-6 EI2579

    SN-6是选择性 Na+/Ca2+ 离子交换抑制剂。

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  • SKF 38393 hydrobromide EI2564

    SKF 38393 hydrobromide是选择性 D1样激动剂。

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  • SCH 39166 hydrobromide EI2508

    SCH 39166 hydrobromide是高亲和性 D1/D5 受体拮抗剂。

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  • SCH 23390 hydrochloride EI2506

    SCH 23390 hydrochloride是经典的选择性 D1样拮抗剂， 也是5-HT2C和5-HT1C的激动剂，Kir3的通道阻断剂。

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