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Ion Pumps/Transporters


Ion pumps/transporters are transmembrane proteins that allow ion flux across biological membranes against their concentration gradient. Ion pumps require energy usually from ATP hydrolysis, whilst exchangers use the energy established by the concentration gradient of another ion. They belong to the ATPase and solute carrier families and are important for maintaining the correct concentrations of various ions within the appropriate subcellular and intercellular compartments. Ion pumps/transporters include:
Ca2+-ATPase ;    H+,K+-ATPase;    H+-ATPase;    K+/Cl- Cotransporter 2 ;   Monocarboxylate Transporters;
Na+/Ca2+ Exchanger ;   Na+/H+ Exchanger ;   Na+/K+ ATPase ;   Na+/K+/Cl- Symporter.

  • (±)-McN 5652 EI0090

    (±)-McN 5652是活性的， 口服活性的5-HT 吸收抑制剂。体外也能抑制 noradrenalin，dopamine的吸收。

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  • (+)-UH 232 maleate EI0072

    (+)-UH 232 maleate是D2 自主受体拮抗剂。 也是D3 部分激动剂。

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  • (+)-PD 128907 hydrochloride EI0068

    (+)-PD 128907 hydrochloride是D3 激动剂 (D3 ≥ D2 > D4)。

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  • (+)-AJ 76 hydrochloride EI0063

    (+)-AJ 76 hydrochloride是拮抗剂， 优先作用于 D2-样自主受体。

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  • (-)-Quinpirole hydrochloride EI0060

    (-)-Quinpirole hydrochloride是选择性 D2-样激动剂。

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