GABA Receptor


GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. GABA receptors influence cognition by coordinating with glutamatergic processes. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels; whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors. A subclass of ionotropic GABA receptors, insensitive to typical allosteric modulators of GABAA receptor channels such as benzodiazepines and barbiturates, designated GABAС receptor.
  • 17-PA EI0217

    17-PA是Neurosteroid activation的拮抗剂,direct gating of GABAA。

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  • (S)-SNAP 5114 EI0164

    (S)-SNAP 5114是GABA uptake inhibitor(摄取抑制剂)。

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  • (RS)-Baclofen EI0139

    (RS)-Baclofen是选择性 GABAB 激动剂。

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  • (±)-Nipecotic acid EI0094

    (±)-Nipecotic acid是GABA uptake inhibitor(摄取抑制剂)。

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  • (-)-Bicuculline methochloride EI0053

    (-)-Bicuculline methochloride是水溶性 GABAA 拮抗剂。

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  • 17-PA EI0217

    17-PA是Neurosteroid activation的拮抗剂,direct gating of GABAA。

    More
  • (S)-SNAP 5114 EI0164

    (S)-SNAP 5114是GABA uptake inhibitor(摄取抑制剂)。

    More
  • (RS)-Baclofen EI0139

    (RS)-Baclofen是选择性 GABAB 激动剂。

    More
  • (±)-Nipecotic acid EI0094

    (±)-Nipecotic acid是GABA uptake inhibitor(摄取抑制剂)。

    More
  • (-)-Bicuculline methochloride EI0053

    (-)-Bicuculline methochloride是水溶性 GABAA 拮抗剂。

    More
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