CRM1
CRM1 (chromosomal maintenance 1,Exportin 1 (XPO1)) is an eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA. Exportin 1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
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S 18986是AMPA阳性变构的调节剂(positive allosteric modulator)。
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Piracetam是 益智活性可以调节AMPA 受体上的钠离子通量(Na+-flux)。
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Philanthotoxin 74是GluR1,GluR3 AMPA 受体拮抗剂。
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PF 4778574是 AMPA 受体阳性变构的调节剂(positive allosteric modulator)。
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NBQX disodium salt是活性的 AMPA 拮抗剂。NBQX 的稳定性水溶性状态。。
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