PPAR
PPARs (peroxisome proliferator-activated receptors) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis of higher organisms.
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GW501516是高活性PPARβ/δ选择性激动剂,EC50为1 nM,比对hPPARα和hPPARγ的抑制性强1000倍。
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Fenofibrate是PPARα激动剂,对小鼠和人的PPARα的EC50分别为18 μM和30 μM。
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GW501516是高活性PPARβ/δ选择性激动剂,EC50为1 nM,比对hPPARα和hPPARγ的抑制性强1000倍。
More
-
Fenofibrate是PPARα激动剂,对小鼠和人的PPARα的EC50分别为18 μM和30 μM。
More