mAChR


MAChRs (Muscarinic acetylcholine receptors) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors were named as such because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists.
  • PTAC oxalate EI2270

    PTAC oxalate是Muscarinic 受体配体,在其不同的亚型上会展现部分激动或者拮抗的活性。

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  • Pirenzepine dihydrochloride EI2178

    Pirenzepine dihydrochloride是选择性 M1 muscarinic 受体拮抗剂。

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  • PD 102807 EI2068

    PD 102807是选择性 M4 拮抗剂。

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  • Oxotremorine M EI2031

    Oxotremorine M是毒蕈碱受体激动剂(muscarinic)。

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  • Oxotremorine sesquifumarate EI2032

    Oxotremorine sesquifumarate是毒蕈碱受体激动剂(muscarinic)。

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  • PTAC oxalate EI2270

    PTAC oxalate是Muscarinic 受体配体,在其不同的亚型上会展现部分激动或者拮抗的活性。

    More
  • Pirenzepine dihydrochloride EI2178

    Pirenzepine dihydrochloride是选择性 M1 muscarinic 受体拮抗剂。

    More
  • PD 102807 EI2068

    PD 102807是选择性 M4 拮抗剂。

    More
  • Oxotremorine M EI2031

    Oxotremorine M是毒蕈碱受体激动剂(muscarinic)。

    More
  • Oxotremorine sesquifumarate EI2032

    Oxotremorine sesquifumarate是毒蕈碱受体激动剂(muscarinic)。

    More
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