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Leukotriene Receptor


The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins:
Leukotriene B4 receptors (BLTRs) - bind to and are activated by LTB4:
BLT1 (Leukotriene B4 receptor 1) - LTB4R
BLT2 (Leukotriene B4 receptor 2) - LTB4R2
Cysteinyl leukotriene receptors (CysLTRs) - bind to and are activated by LTC4, LTD4, and LTE4:
CysLT1 (Cysteinyl leukotriene receptor 1) - CYSLTR1
CysLT2 (Cysteinyl leukotriene receptor 2) - CYSLTR2
The recently elucidated CysLTE, represented by GPR99/OXGR1, may constitute a third CysLTR.

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