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P2Y Receptor


P2Y receptors are a family of purinergic G protein-coupled receptors, stimulated by nucleotides such as ATP, ADP, UTP, UDP and UDP-glucose. To date, 8 P2Y receptors have been cloned in humans: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13 and P2Y14. P2Y receptors are present in almost all human tissues where they exert various biological functions based on their G-protein coupling.

  • Prasugrel EY1266

    Prasugrel是ADP受体抑制剂，能通过不可逆的与P2Y12受体结合降低血小板的聚集。

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  • A-438079 HCl EY1067

    A-438079盐酸盐是P2X7受体拮抗剂，能抑制人重组P2X7细胞系的钙流，pIC50为6.9。

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  • MRS 2578 EY0351

    MRS2578是P2Y6受体拮抗剂，IC50为37 nM，对P2Y1，P2Y2，P2Y4和P2Y11受体的抑制性较弱。

    More

  • Prasugrel EY1266

    Prasugrel是ADP受体抑制剂，能通过不可逆的与P2Y12受体结合降低血小板的聚集。

    More

  • A-438079 HCl EY1067

    A-438079盐酸盐是P2X7受体拮抗剂，能抑制人重组P2X7细胞系的钙流，pIC50为6.9。

    More

  • MRS 2578 EY0351

    MRS2578是P2Y6受体拮抗剂，IC50为37 nM，对P2Y1，P2Y2，P2Y4和P2Y11受体的抑制性较弱。

    More
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