mAChR
MAChRs (Muscarinic acetylcholine receptors) are acetylcholine receptors that form G protein-receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors were named as such because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists.
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Cevimeline hydrochloride是选择性 M1 激动剂。
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Biperiden hydrochloride是Muscarinic 受体拮抗剂， 对M1有一些选择活性。
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Arecaidine propargyl ester tosylate是Muscarinic 激动剂。
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AQ-RA 741是选择性， 高亲和性 M2 拮抗剂。
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AF-DX 384是活性的 M2/M4 拮抗剂。
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Cevimeline hydrochloride是选择性 M1 激动剂。
More
-
Biperiden hydrochloride是Muscarinic 受体拮抗剂， 对M1有一些选择活性。
More
-
Arecaidine propargyl ester tosylate是Muscarinic 激动剂。
More
-
AQ-RA 741是选择性， 高亲和性 M2 拮抗剂。
More
-
AF-DX 384是活性的 M2/M4 拮抗剂。
More
