Dopamine Receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling. Abnormal dopamine receptor signaling and dopaminergic nerve function is implicated in several neuropsychiatric disorders. Thus, dopamine receptors are common neurologic drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The D1 and D5 receptors are members of the D1-like family of dopamine receptors, whereas the D2, D3 and D4 receptors are members of the D2-like family.
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SB 277011A dihydrochloride是选择性 D3 拮抗剂。
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Roxindole hydrochloride是Roxindole hydrochloride is a dopamine D2 autoreceptor agonist and has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter.。
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Ropinirole是选择性 D2样激动剂。
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Ro 10-5824 dihydrochloride是选择性 D4 受体部分激动剂。
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Raclopride是活性选择性 D2/D3 拮抗剂。
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SB 277011A dihydrochloride是选择性 D3 拮抗剂。
More
-
Roxindole hydrochloride是Roxindole hydrochloride is a dopamine D2 autoreceptor agonist and has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter.。
More
-
Ropinirole是选择性 D2样激动剂。
More
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Ro 10-5824 dihydrochloride是选择性 D4 受体部分激动剂。
More
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Raclopride是活性选择性 D2/D3 拮抗剂。
More
