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nAChR


nAChRs (Nicotinic acetylcholine receptors) are neuron receptor proteins that respond to the neurotransmitter acetylcholine. They are particularly responsive to nicotine.  Nicotinic receptors also respond to drugs, including the nicotinic receptor agonist nicotine. As ionotropic receptors, nAChRs are directly linked to ion channels and do not use second messengers (as metabotropic receptors do). Nicotinic acetylcholine receptors are the best-studied of the ionotropic receptors.

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    4-Acetyl-1，1-dimethylpiperazinium iodide是Nicotinic 激动剂。

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  • 3-pyr-Cytisine EI0271

    3-pyr-Cytisine是α4β2 受体的高亲和性， 部分激动剂。

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  • 3-Bromocytisine EI0263

    3-Bromocytisine是α4β4， α4β2 and α7 nACh 受体的活性激动剂 。

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  • 1-Acetyl-4-methylpiperazine hydrochloride EI0219

    1-Acetyl-4-methylpiperazine hydrochloride是Nicotinic 激动剂。

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  • (±)-Epibatidine EI0083

    (±)-Epibatidine是高亲和性 nicotinic 激动剂。

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