nAChR
nAChRs (Nicotinic acetylcholine receptors) are neuron receptor proteins that respond to the neurotransmitter acetylcholine. They are particularly responsive to nicotine. Nicotinic receptors also respond to drugs, including the nicotinic receptor agonist nicotine. As ionotropic receptors, nAChRs are directly linked to ion channels and do not use second messengers (as metabotropic receptors do). Nicotinic acetylcholine receptors are the best-studied of the ionotropic receptors.
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Desformylflustrabromine hydrochloride是α4β2的阳性变构的调节剂（positive allosteric modulator）, 也是muscle-type nAChR的抑制剂。
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Chlorisondamine diiodide是Nicotinic 拮抗剂。
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CC4
EI0704
CC4是高亲和性，具有亚型选择性的α6β2和α4β2部分激动剂。
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bPiDDB是Orthosteric nAChR 拮抗剂。
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Bisindolylmaleimide II是活性的 PKC 抑制剂，nicotinic 受体拮抗剂。
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