EGFR


The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.
The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
  • BIBU 1361 dihydrochloride EI0572

    BIBU 1361 dihydrochloride是EGFR-激酶的选择性的抑制剂。

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  • AG 555 EI0398

    AG 555是活性的 EGFR-激酶抑制剂。

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  • AG 494 EI0397

    AG 494是活性的 EGFR-激酶抑制剂。

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  • AG 1478 hydrochloride EI0396

    AG 1478 hydrochloride是高 活性的 EGFR-激酶抑制剂。

    More
  • ASP8273 EY2847

    ASP8273 is a small molecule, irreversible TKI inhibitor that inhibits the kinase activity of EGFR mutations including T790M, with limited activity against EGFR wild-type NSCLC. In the in vitro enzymatic and cell-based assays, ASP8273 were evaluated against EGFR mutantsand WT EGFR.

    More
  • BIBU 1361 dihydrochloride EI0572

    BIBU 1361 dihydrochloride是EGFR-激酶的选择性的抑制剂。

    More
  • AG 555 EI0398

    AG 555是活性的 EGFR-激酶抑制剂。

    More
  • AG 494 EI0397

    AG 494是活性的 EGFR-激酶抑制剂。

    More
  • AG 1478 hydrochloride EI0396

    AG 1478 hydrochloride是高 活性的 EGFR-激酶抑制剂。

    More
  • ASP8273 EY2847

    ASP8273 is a small molecule, irreversible TKI inhibitor that inhibits the kinase activity of EGFR mutations including T790M, with limited activity against EGFR wild-type NSCLC. In the in vitro enzymatic and cell-based assays, ASP8273 were evaluated against EGFR mutantsand WT EGFR.

    More
  • BIBU 1361 dihydrochloride EI0572

    BIBU 1361 dihydrochloride是EGFR-激酶的选择性的抑制剂。

    More
  • AG 555 EI0398

    AG 555是活性的 EGFR-激酶抑制剂。

    More
  • AG 494 EI0397

    AG 494是活性的 EGFR-激酶抑制剂。

    More
  • AG 1478 hydrochloride EI0396

    AG 1478 hydrochloride是高 活性的 EGFR-激酶抑制剂。

    More
  • ASP8273 EY2847

    ASP8273 is a small molecule, irreversible TKI inhibitor that inhibits the kinase activity of EGFR mutations including T790M, with limited activity against EGFR wild-type NSCLC. In the in vitro enzymatic and cell-based assays, ASP8273 were evaluated against EGFR mutantsand WT EGFR.

    More
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