PKC
PKC (Protein kinase C) is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family. PKC enzymes in turn are activated by signals such as increases in the concentration of diacylglycerol (DAG) or calcium ions (Ca2+). Hence PKC enzymes play important roles in several signal transduction cascades.
The PKC family consists of fifteen isozymes in humans. They are divided into three subfamilies, based on their second messenger requirements: conventional (or classical), novel, and atypical.
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Rottlerin是有报道的PKCδ抑制剂。
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Ro 32-0432 hydrochloride是活性的口服有效的 PKC 抑制剂。
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R 59-022是Diacylglycerol 激酶抑制剂， 同时可以增强protein kinase C ( PKC ) 的活性。
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Prostratin是PKC的激动剂， 也是NF-κB的激动剂。
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PEP 005是Protein kinase C 激动剂。
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Rottlerin是有报道的PKCδ抑制剂。
More
-
Ro 32-0432 hydrochloride是活性的口服有效的 PKC 抑制剂。
More
-
R 59-022是Diacylglycerol 激酶抑制剂， 同时可以增强protein kinase C ( PKC ) 的活性。
More
-
Prostratin是PKC的激动剂， 也是NF-κB的激动剂。
More
-
PEP 005是Protein kinase C 激动剂。
More
