Hedgehog
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma.
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Ciliobrevin A是Hedgehog (Hh) pathway 拮抗剂， 抑制 ciliogenesis， 也抑制 dynein。
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AY 9944 dihydrochloride是Hedgehog (Hh) signaling的抑制剂。抑制Δ7-dehydrocholesterol还原酶。
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20(S)-Hydroxycholesterol是Hedgehog (Hh) signaling 的变构的激动剂， induces Smo(Smoothened) accumulation。
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U 18666A是Hedgehog (Hh) 信号通路抑制剂。 也抑制胆固醇的合成(cholesterol synthesis)。
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SAG
EI2439
SAG是活性的Smoothened receptor的激动剂，可以激活Hedgehog信号通路。
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